TREATMENT OF NAUSEA WITH EXTRADURAL DROPERIDOL
نویسندگان
چکیده
منابع مشابه
Chlorpromazine, placebo and droperidol in the treatment of nausea and vomiting associated with cisplatin therapy.
The use of cisplatin may be associated with severe nausea and vomiting. Two separate, randomized, double-blind trials, comparing the anti-emetic effect of chlorpromazine with placebo and chlorpromazine with droperidol, were conducted in patients receiving cisplatin for ovarian cancer. Chlorpromazine was statistically superior to placebo in the control of nausea and vomiting in those patients tr...
متن کاملOndansetron-droperidol combination vs. ondansetron or droperidol monotherapy in the prevention of postoperative nausea and vomiting
INTRODUCTION Laparoscopic cholecystectomy is associated with a high incidence of postoperative nausea and vomiting. In this study we investigated comparatively the efficacy of combination therapy with ondansetron plus droperidol versus monotherapy with each agent alone in preventing postoperative nausea and vomiting following elective laparoscopic cholecystectomy. MATERIAL AND METHODS One hun...
متن کاملProlongation of QTc interval after postoperative nausea and vomiting treatment by droperidol or ondansetron.
BACKGROUND At dosages above 0.1 mg/kg, droperidol induces a dose-dependent QTc interval prolongation. Although subject to controversy, low-dose droperidol has recently been suspected to induce cardiac arrhythmias. Hence, 5-hydroxytryptamine type 3 antagonists have become the first-line drug for management of postoperative nausea and vomiting. These drugs are also known to prolong the QTc interv...
متن کاملDroperidol has comparable clinical efficacy against both nausea and vomiting.
BACKGROUND Droperidol is commonly noted to be more effective at preventing postoperative nausea (PON) than vomiting (POV) and it is assumed to have a short duration of action. This may be relevant for clinical decisions, especially for designing multiple-drug antiemetic regimens. METHODS We conducted a post hoc analysis of a large multicentre trial. Within this trial, 1734 patients underwent ...
متن کامل[Controlled trial of dexamethasone compared with droperidol and ondansetron for the treatment of postoperative nausea and vomiting].
BACKGROUND Dexamethasone is useful as prophylaxis for postoperative nausea and vomiting (PONV). AIM To study the short term efficacy of dexamethasone to treat PONV in adults without prophylaxis, and compare its efficacy with that of droperidol and ondansetron. MATERIAL AND METHODS A prospective study was performed with 120 consecutive adult patients presenting PONV in the postanesthesia car...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1986
ISSN: 0007-0912
DOI: 10.1093/bja/58.10.1202